Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536712 | 1.00 | LMNA (0.52) | LMNATAS1R3TAS1R1TAS1R2CHRM4 | |
| SCHEMBL11538814 | 1.00 | LMNA (0.52) | LMNATAS1R3TAS1R1TAS1R2CHRM4 | |
| SCHEMBL11537335 | 0.98 | LMNA (0.50) | LMNATAS1R3TAS1R1TAS1R2CHRM4 | |
| SCHEMBL11538275 | 0.92 | LMNA (0.50) | LMNACHRM4NPC1RAB9AALDH1A1 | |
| SCHEMBL11538234 | 0.86 | NPC1 (0.52) | LMNATAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL11535873 | 0.84 | KMT2A (0.44) | LMNANPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL11537657 | 0.81 | TAS1R3 (0.51) | LMNATAS1R3TAS1R1TAS1R2KMT2A | |
| SCHEMBL11535293 | 0.79 | NPC1 (0.48) | LMNATAS1R3TAS1R1TAS1R2MLLT1 | |
| SCHEMBL10825856 | 0.78 | CHRM4 (0.49) | LMNACHRM4NPC1RAB9AHPGD | |
| SCHEMBL11263887 | 0.76 | LMNA (0.42) | LMNANPC1RAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | claimed |
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |