Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266333 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDHDAC6HDAC1HDAC8 | |
| SCHEMBL5461482 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2GLAHPGDHDAC6 | |
| SCHEMBL11276434 | 0.81 | HDAC6 (0.54) | ALDH1A1SMN1; SMN2GLAHPGDHDAC6 | |
| SCHEMBL760729 | 0.78 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2HPGDHDAC6RECQL | |
| SCHEMBL11272498 | 0.78 | HPGD (0.46) | SMN1; SMN2HPGDHDAC6HDAC1HDAC8 | |
| SCHEMBL19034792 | 0.78 | HCAR3 (0.53) | SMN1; SMN2HPGDHDAC6HDAC1HDAC8 | |
| SCHEMBL14220982 | 0.76 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2GLAHPGDHDAC6 | |
| SCHEMBL28871141 | 0.76 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2GLAHPGDHDAC6 | |
| Hydrochloric Acid SCHEMBL9663652 | 0.74 | HSD17B10 (0.53) | ALDH1A1SMN1; SMN2GLAHPGDHDAC6 | |
| SCHEMBL8471293 | 0.73 | KDM4E (0.68) | ALDH1A1SMN1; SMN2GLAHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |