Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263886 | 0.96 | TP53 (0.33) | TP53ALDH1A1LMNATSHRCHRM2 | |
| SCHEMBL11261141 | 0.96 | TP53 (0.36) | TP53ALDH1A1LMNATSHRCHRM2 | |
| Hydrochloric Acid SCHEMBL11270834 | 0.95 | LMNA (0.36) | TP53ALDH1A1LMNATSHRCHRM2 | |
| SCHEMBL11261826 | 0.94 | TSHR (0.36) | TP53ALDH1A1LMNATSHRCHRM2 | |
| SCHEMBL11262419 | 0.94 | MEN1 (0.33) | TP53ALDH1A1LMNACYP3A4KCNH2 | |
| SCHEMBL11252916 | 0.94 | MEN1 (0.33) | TP53ALDH1A1LMNACYP3A4KCNH2 | |
| SCHEMBL11257397 | 0.93 | ABCB11 (0.32) | TP53ALDH1A1LMNATSHRCYP3A4 | |
| SCHEMBL11255797 | 0.93 | KMT2A (0.32) | TP53ALDH1A1LMNACYP3A4KCNH2 | |
| SCHEMBL11266996 | 0.93 | TP53 (0.32) | TP53ALDH1A1LMNACYP3A4KCNH2 | |
| SCHEMBL11262177 | 0.93 | TP53 (0.32) | TP53ALDH1A1LMNACYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |