SCHEMBL11265398

SCHEMBL11265398

COC(C)OC(CCl)CCC=C(C)C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.40
ALDH1A1 P00352 3/20 0.40
TSHR P16473 1/20 0.37
SRC P12931 1/20 0.33
NFE2L2 Q16236 1/20 0.31
MEN1 O00255 1/20 0.30
RECQL P46063 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11267075 0.85 LMNA (0.39) ALOX15ALDH1A1TSHRSRC
SCHEMBL11261375 0.83 ALOX15 (0.36) ALOX15ALDH1A1TSHRSRC
SCHEMBL11276569 0.82 ALOX15 (0.40) ALOX15ALDH1A1TSHRSRC
SCHEMBL11271413 0.80 ALOX15 (0.35) ALOX15ALDH1A1TSHR
SCHEMBL11281561 0.75 CYP2D6 (0.33)
SCHEMBL11278123 0.73 ALOX15 (0.37) ALOX15ALDH1A1TSHRNFE2L2
SCHEMBL17131606 0.70 ALOX15 (0.50) ALOX15ALDH1A1TSHRSRCKMT2A
SCHEMBL11272333 0.68 LMNA (0.39) ALOX15ALDH1A1TSHRSRC
SCHEMBL872808 0.68 ALOX15 (0.57) ALOX15ALDH1A1TSHRNFE2L2
SCHEMBL11689424 0.67 ALOX15 (0.47) ALOX15ALDH1A1TSHRSRCKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0054909-A2 9-Halo-8-hydroxy-4-methyl-4-nonenoic acids, derivatives thereof and a process for their preparation MITSUBISHI KASEI CORPORATION (JP) 1982-06-30 EP disclosed