Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725601 | 0.86 | KDR (0.43) | KDRLMNAGRM4RAPGEF3RAPGEF4 | |
| SCHEMBL11609759 | 0.71 | PDE2A (0.46) | TSHRCYP3A4MAPK1TDP1MAPT | |
| SCHEMBL23959825 | 0.71 | MEN1 (0.57) | TSHRCYP3A4MAPTNPSR1MEN1 | |
| SCHEMBL8336230 | 0.71 | APEX1 (0.65) | TSHRTDP1KDRMEN1KMT2A | |
| SCHEMBL11600693 | 0.69 | PDE2A (0.57) | TSHRCYP3A4MAPK1TDP1MAPT | |
| SCHEMBL11606729 | 0.69 | TSHR (0.40) | TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL3043251 | 0.67 | TRPV4 (0.46) | TSHRCYP3A4MAPK1TDP1LMNA | |
| SCHEMBL11414045 | 0.67 | KDR (0.47) | KDRLMNAGRM4RAPGEF3RAPGEF4 | |
| SCHEMBL11525237 | 0.67 | KDR (0.43) | TDP1KDRMAPTNPC1LMNA | |
| SCHEMBL19089350 | 0.67 | AR (0.45) | KDRLMNAGRM4RAPGEF3RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318919-A | Combating bacteria with tetrachlorophthalamic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |