Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | RAPGEF3 | O95398 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265425 | 0.86 | TSHR (0.36) | KDRGRM4RAPGEF4PDK1CNR1 | |
| SCHEMBL11414045 | 0.80 | KDR (0.47) | KDRGRM4RAPGEF4PDK1CNR1 | |
| SCHEMBL11525237 | 0.80 | KDR (0.43) | KDRGRM4RAPGEF4PDK1CNR1 | |
| SCHEMBL19089350 | 0.80 | AR (0.45) | KDRGRM4RAPGEF4PDK1CNR1 | |
| SCHEMBL10389130 | 0.78 | RAPGEF3 (0.42) | KDRGRM4RAPGEF4PDK1CNR1 | |
| SCHEMBL20656067 | 0.77 | RAPGEF3 (0.41) | KDRGRM4RAPGEF4PDK1CNR1 | |
| SCHEMBL11595628 | 0.77 | KDR (0.49) | KDRGRM4PDK1TRPV1FLT1 | |
| SCHEMBL20655719 | 0.76 | AR (0.49) | KDRGRM4RAPGEF4PDK1CNR1 | |
| SCHEMBL4556067 | 0.76 | KDR (0.75) | KDRPDK1TRPV1LMNABRAF | |
| SCHEMBL25698906 | 0.76 | KDR (0.40) | KDRGRM4RAPGEF4PDK1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095032-A | PARASITICIDAL NEW SUBSTITUTED THIENOPYRANONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| US-4804655-A | Pesticidal cyclic malonylphosphonic diamides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| US-4771048-A | VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |
| US-4766144-A | 3-carbamoyl-4-hydroxy-coumarins for combating parasitic heiminths | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-23 | — | — | US | disclosed |
| US-4459304-A | MITICIDES, NEMATOCIDES, FUNGICIDES, BACTERICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-10 | — | — | US | disclosed |
| US-4318919-A | Combating bacteria with tetrachlorophthalamic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |
| US-4293566-A | FUNGICIDES, BACTERICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |
| US-4183949-A | Pesticidally active 1-arylamino-2,4-dinitronaphthalenes | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-15 | — | — | US | disclosed |