Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246830 | 0.85 | KMT2A (0.52) | KMT2AMAPK1SMN1; SMN2HTTMEN1 | |
| SCHEMBL11244923 | 0.84 | KMT2A (0.59) | KMT2AMAPTNPC1RAB9AMAPK1 | |
| SCHEMBL4781020 | 0.80 | KMT2A (0.58) | KMT2AMEN1ALOX15CXCR2 | |
| SCHEMBL4781017 | 0.80 | KMT2A (0.58) | KMT2AMEN1ALOX15CXCR2 | |
| SCHEMBL2086872 | 0.75 | KMT2A (0.56) | KMT2AMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL2086875 | 0.75 | KMT2A (0.56) | KMT2AMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL2087129 | 0.74 | KMT2A (0.80) | KMT2AMAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL3402743 | 0.74 | KMT2A (0.80) | KMT2AMAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL2087128 | 0.74 | KMT2A (0.80) | KMT2AMAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL11174716 | 0.74 | KMT2A (0.58) | KMT2AMAPTNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321393-A | Method for preparing 2-cyanamidobenzimidazoles or 2-cyanamidobenzoxazoles | SMITHKLINE CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4285878-A | N-Phenyl-N'-cyano-O-phenylisoureas | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |