Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265660 | 0.84 | KMT2A (0.52) | KMT2AMAPTMEN1HTTLMNA | |
| SCHEMBL11246830 | 0.84 | KMT2A (0.52) | KMT2AMEN1HTTSMN1; SMN2P2RX3 | |
| SCHEMBL11174716 | 0.84 | KMT2A (0.58) | KMT2AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL4781017 | 0.84 | KMT2A (0.58) | KMT2AMEN1ALOX15P2RX3IMPDH2 | |
| SCHEMBL4781020 | 0.84 | KMT2A (0.58) | KMT2AMEN1ALOX15P2RX3IMPDH2 | |
| SCHEMBL2086875 | 0.81 | KMT2A (0.56) | KMT2AMAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL9954599 | 0.81 | KMT2A (0.56) | KMT2AMAPTMEN1KDM4EHPGD | |
| SCHEMBL9954596 | 0.81 | KMT2A (0.56) | KMT2AMAPTMEN1KDM4EHPGD | |
| SCHEMBL2086872 | 0.81 | KMT2A (0.56) | KMT2AMAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL3402743 | 0.81 | KMT2A (0.80) | KMT2AMAPTLMNASMN1; SMN2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321393-A | Method for preparing 2-cyanamidobenzimidazoles or 2-cyanamidobenzoxazoles | SMITHKLINE CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4285878-A | N-Phenyl-N'-cyano-O-phenylisoureas | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |