Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ARG1 | P05089 | 2/20 | 0.55 |
| ▸ | ARG2 | P78540 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12583604 | 1.00 | HIF1A (0.60) | HIF1ASMN1; SMN2ARG1ARG2SLC6A2 | |
| SCHEMBL1842425 | 1.00 | HIF1A (0.60) | HIF1ASMN1; SMN2ARG1ARG2SLC6A2 | |
| SCHEMBL8351006 | 0.88 | SMN1; SMN2 (0.69) | HIF1ASMN1; SMN2ARG1ARG2SLC6A2 | |
| SCHEMBL2212930 | 0.85 | SMN1; SMN2 (0.60) | HIF1ASMN1; SMN2ARG1ARG2SLC6A2 | |
| SCHEMBL366770 | 0.82 | SMN1; SMN2 (0.62) | HIF1ASMN1; SMN2ARG1ARG2SLC6A2 | |
| SCHEMBL7924236 | 0.82 | SMN1; SMN2 (0.62) | HIF1ASMN1; SMN2ARG1ARG2SLC6A2 | |
| SCHEMBL22190022 | 0.82 | SMN1; SMN2 (0.62) | HIF1ASMN1; SMN2ARG1ARG2SLC6A2 | |
| SCHEMBL366771 | 0.82 | SMN1; SMN2 (0.62) | HIF1ASMN1; SMN2ARG1ARG2SLC6A2 | |
| SCHEMBL29278348 | 0.81 | ARG1 (0.60) | HIF1ASMN1; SMN2ARG1ARG2SLC6A2 | |
| SCHEMBL343695 | 0.81 | ARG1 (0.60) | HIF1ASMN1; SMN2ARG1ARG2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339589-A | Preparation of 4-substituted oxazolidin-5-ones | BASF AKTIENGESELLSCHAFT (DE) | 1982-07-13 | — | — | US | disclosed |
| US-4264771-A | Alkylation of substituted oxazolinone-(5) compounds | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |