Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ARG1 | P05089 | 2/20 | 0.57 |
| ▸ | ARG2 | P78540 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924236 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2HIF1AARG1ARG2SLC6A2 | |
| SCHEMBL366770 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2HIF1AARG1ARG2SLC6A2 | |
| SCHEMBL8351006 | 0.90 | SMN1; SMN2 (0.69) | SMN1; SMN2HIF1AARG1ARG2SLC6A2 | |
| SCHEMBL7235580 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1AARG1ARG2SLC6A2 | |
| SCHEMBL7235584 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1AARG1ARG2SLC6A2 | |
| SCHEMBL3117431 | 0.85 | BLM (0.61) | SMN1; SMN2HIF1AARG1ARG2BLM | |
| SCHEMBL10778604 | 0.85 | BLM (0.61) | SMN1; SMN2HIF1AARG1ARG2BLM | |
| SCHEMBL3117439 | 0.85 | BLM (0.61) | SMN1; SMN2HIF1AARG1ARG2BLM | |
| SCHEMBL22190022 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2HIF1AARG1ARG2SLC6A2 | |
| SCHEMBL22689266 | 0.82 | ARG1 (0.79) | SMN1; SMN2HIF1AARG1ARG2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109219592-A | Benzyl phenylate analog derivative and its preparation method and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2019-01-15 | — | — | CN | claimed |
| CN-107417572-A | Benzyl phenylate analog derivative and its preparation method and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2017-12-01 | — | — | CN | claimed |
| EP-2239335-B1 | PROCESS FOR PRODUCTION OF SERINE DERIVATIVE, AND PROTEIN FOR USE IN THE PROCESS | AJINOMOTO KK (JP) | 2013-02-27 | — | — | EP | claimed |
| US-8372607-B2 | Method for producing serine derivative and protein used for the same | AJINOMOTO CO., INC. (JP) | 2013-02-12 | — | — | US | claimed |
| US-20100317068-A1 | METHOD FOR PRODUCING SERINE DERIVATIVE AND PROTEIN USED FOR THE SAME | AJINOMOTO CO., INC. (JP) | 2010-12-16 | — | — | US | claimed |
| EP-2239335-A1 | PROCESS FOR PRODUCTION OF SERINE DERIVATIVE, AND PROTEIN FOR USE IN THE PROCESS | Ajinomoto Co., Inc. (JP) | 2010-10-13 | — | — | EP | claimed |
| CN-109219592-A | Benzyl phenylate analog derivative and its preparation method and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2019-01-15 | — | — | CN | disclosed |
| CN-107417572-A | Benzyl phenylate analog derivative and its preparation method and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2017-12-01 | — | — | CN | disclosed |
| CN-101367794-B | Preparation method for quinazoline derivants and medical uses thereof | SHANGHAI HENGRUI PHARM CO LTD | 2013-07-10 | — | — | CN | disclosed |
| EP-2593471-A1 | CYCLOTETRAPEPTIDES WITH PRO-ANGIOGENIC PROPERTIES | GENETADI Biotech, S.L. (ES) | 2013-05-22 | — | — | EP | disclosed |
| EP-2239335-B1 | PROCESS FOR PRODUCTION OF SERINE DERIVATIVE, AND PROTEIN FOR USE IN THE PROCESS | AJINOMOTO KK (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-8372607-B2 | Method for producing serine derivative and protein used for the same | AJINOMOTO CO., INC. (JP) | 2013-02-12 | — | — | US | disclosed |
| WO-2012007562-A1 | CYCLOTETRAPEPTIDES WITH PRO-ANGIOGENIC PROPERTIES | GENETADI BIOTECH, S.L. (ES) | 2012-01-19 | — | — | WO | disclosed |
| US-7348448-B2 | Phenylcarboxylate beta-secretase inhibitors for the treatment of alzheimer's disease | MERCK & CO., INC. (US) | 2008-03-25 | — | — | US | disclosed |
| EP-1864995-A1 | BETA-LACTAMIC RGD CYCLOPEPTIDES CONTAINING GAMMA TURNS | UNIVERSIDAD DEL PAIS VASCO-EUSKAL HERRIKO UNIBERSITATEA (ES) | 2007-12-12 | — | — | EP | disclosed |
| WO-2005004803-A2 | PHENYLCARBOXYLATE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK & CO., INC. (US) | 2005-01-20 | — | — | WO | disclosed |
| EP-0906900-B1 | A process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid | AJINOMOTO KK (JP) | 2002-01-23 | — | — | EP | disclosed |
| US-6028217-A | CHEMICAL INTERMEDIATE FOR RENIN INHIBITOR OR ENKEPHALINASE ENZYME INHIBITOR | AJINOMOTO CO., INC. (JP) | 2000-02-22 | — | — | US | disclosed |
| EP-0906900-A1 | A process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid | Ajinomoto Co., Inc. (JP) | 1999-04-07 | — | — | EP | disclosed |
| CN-1036769-A | The method for preparing Cephem Derivative and intermediate thereof | EISAI CO LTD (JP) | 1989-11-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317068-A1 | METHOD FOR PRODUCING SERINE DERIVATIVE AND PROTEIN USED FOR THE SAME | SPR, AMD1, DAO | SMN1; SMN2 3287/4885HIF1A 3004/4885ARG1 3039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.