Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262923 | 0.86 | PTGER4 (0.48) | ALDH1A1SMN1; SMN2NPC1KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL11275414 | 0.85 | PTGER4 (0.47) | ALDH1A1SMN1; SMN2NPC1KDM4ERAB9A | |
| SCHEMBL11275412 | 0.83 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2NPC1KDM4ERAB9A | |
| SCHEMBL11264995 | 0.80 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2NPC1KDM4ERAB9A | |
| SCHEMBL11264741 | 0.80 | FGFR1 (0.43) | ALDH1A1SMN1; SMN2NPC1KDM4ERAB9A | |
| SCHEMBL11269530 | 0.76 | MAPT (0.46) | ALDH1A1SMN1; SMN2NPC1KDM4ERAB9A | |
| SCHEMBL3569466 | 0.72 | DAO (0.56) | ALDH1A1SMN1; SMN2NPC1KDM4ERAB9A | |
| SCHEMBL30643066 | 0.71 | TYR (0.48) | KDM4E | |
| SCHEMBL10748526 | 0.70 | BCAT2 (0.48) | BCAT2ALDH1A1RAB9APOLBMAPT | |
| SCHEMBL9141016 | 0.69 | BCAT2 (0.47) | BCAT2ALDH1A1KDM4ERAB9AFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |