Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | RORB | Q92753 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466236 | 0.92 | THRA (0.38) | THRATHRBCNR1CNR2APEX1 | |
| SCHEMBL9494786 | 0.85 | CNR1 (0.33) | THRATHRBCNR1CNR2APEX1 | |
| SCHEMBL7951310 | 0.82 | THRA (0.38) | THRATHRBCNR1CNR2APEX1 | |
| SCHEMBL7950291 | 0.82 | THRA (0.38) | THRATHRBCNR1CNR2APEX1 | |
| SCHEMBL7948651 | 0.82 | THRA (0.38) | THRATHRBCNR1CNR2APEX1 | |
| SCHEMBL7942239 | 0.82 | THRA (0.38) | THRATHRBCNR1CNR2APEX1 | |
| SCHEMBL2710799 | 0.82 | THRA (0.38) | THRATHRBCNR1CNR2APEX1 | |
| SCHEMBL7954051 | 0.82 | THRA (0.38) | THRATHRBCNR1CNR2APEX1 | |
| SCHEMBL11428141 | 0.80 | ALDH1A1 (0.41) | CNR1CNR2CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL11428135 | 0.80 | HDAC3 (0.41) | APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348308-A | IMPROVING COLOR STABILITY OF VINYL CHLORIDE POLYMERS | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1982-09-07 | — | — | US | disclosed |
| US-4282141-A | DISCOLORATION INHIBITION FOR VINYL CHLORIDE POLYMERS | ARGUS CHEMICAL CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |