Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271490 | 0.87 | STING1 (0.40) | MTNR1AMTNR1BMAPK1AKR1C3AKR1C2 | |
| SCHEMBL4989684 | 0.84 | L3MBTL1 (0.48) | L3MBTL1MTNR1AMTNR1BAOC3CHEK1 | |
| SCHEMBL7411654 | 0.80 | AOC3 (0.48) | L3MBTL1MTNR1AMTNR1BAOC3 | |
| SCHEMBL5180963 | 0.80 | L3MBTL1 (0.49) | L3MBTL1MTNR1AMTNR1BAOC3CHEK1 | |
| SCHEMBL5778033 | 0.79 | AOC3 (0.50) | L3MBTL1MTNR1AMTNR1BAOC3CHEK1 | |
| SCHEMBL11276741 | 0.79 | KMT2A (0.47) | L3MBTL1MTNR1AMTNR1BAKR1C3AKR1C2 | |
| SCHEMBL21631926 | 0.79 | GABBR2 (0.61) | L3MBTL1MTNR1AMTNR1BAOC3 | |
| SCHEMBL11081355 | 0.78 | AOC3 (0.54) | L3MBTL1MTNR1AMTNR1BAOC3 | |
| SCHEMBL11265857 | 0.76 | L3MBTL1 (0.47) | L3MBTL1MTNR1AMTNR1BAOC3CHEK1 | |
| SCHEMBL5181402 | 0.76 | L3MBTL1 (0.56) | L3MBTL1MTNR1AMTNR1BAOC3CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062019-A1 | New phenyl-perhydroazepines | Aktiebolaget Hässle (SE) | 1982-10-06 | — | — | EP | disclosed |