Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147190 | 0.89 | ALDH1A1 (0.44) | ALDH1A1GAAPOLBNPSR1RXRA | |
| SCHEMBL12971677 | 0.75 | ALDH1A1 (0.59) | ALDH1A1GAAPOLBNPSR1CA12 | |
| SCHEMBL11483413 | 0.73 | ALDH1A1 (0.37) | ALDH1A1GAAPOLBNPSR1TDP1 | |
| SCHEMBL11274868 | 0.70 | ALDH1A1 (0.54) | ALDH1A1GAAPOLBNPSR1CA12 | |
| SCHEMBL862542 | 0.70 | ALDH1A1 (0.53) | ALDH1A1GAAPOLBNPSR1TDP1 | |
| SCHEMBL11275604 | 0.70 | ALDH1A1 (0.53) | ALDH1A1GAAPOLBNPSR1CA12 | |
| SCHEMBL12802981 | 0.70 | ALDH1A1 (0.53) | ALDH1A1GAAPOLBNPSR1CA12 | |
| SCHEMBL11267711 | 0.69 | ALDH1A1 (0.58) | ALDH1A1GAAPOLBNPSR1TDP1 | |
| SCHEMBL11423461 | 0.69 | KDM4E (0.33) | ALDH1A1MAPT | |
| SCHEMBL17714637 | 0.68 | ALDH1A1 (0.52) | ALDH1A1GAAPOLBNPSR1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010441-B1 | THE USE OF SYMMETRICALLY SUBSTITUTED PYROMELLITIC DIIMIDES AS RUMINANT FEED ADDITIVES. COMPOSITIONS CONTAINING THESE FEED ADDITIVES | MERCK & CO. INC. (US) | 1982-04-21 | — | — | EP | disclosed |
| US-4212880-A | INCREASE FEED EFFICIENCY | MERCK & CO., INC. (US) | 1980-07-15 | — | — | US | disclosed |