Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266034 | 0.89 | ALDH1A1 (0.53) | ALDH1A1GAAPOLBNPSR1RXRA | |
| SCHEMBL11483413 | 0.84 | ALDH1A1 (0.37) | ALDH1A1GAAPOLBNPSR1TDP1 | |
| SCHEMBL11146401 | 0.80 | ALDH1A1 (0.48) | ALDH1A1GAAPOLBNPSR1TDP1 | |
| SCHEMBL11149357 | 0.77 | ALDH1A1 (0.44) | ALDH1A1GAAPOLBNPSR1CA12 | |
| SCHEMBL11149438 | 0.77 | ALDH1A1 (0.44) | ALDH1A1GAAPOLBNPSR1CA12 | |
| SCHEMBL11149457 | 0.77 | ALDH1A1 (0.44) | ALDH1A1GAAPOLBNPSR1RXRA | |
| SCHEMBL29674635 | 0.76 | ALDH1A1 (0.79) | ALDH1A1GAAPOLBNPSR1KDM4E | |
| SCHEMBL29674594 | 0.76 | MPO (0.49) | ALDH1A1GAATDP1KDM4E | |
| SCHEMBL11148463 | 0.76 | ALDH1A1 (0.44) | ALDH1A1GAAPOLBNPSR1CA12 | |
| SCHEMBL13812446 | 0.76 | ALDH1A1 (0.47) | ALDH1A1GAAPOLBNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010440-B1 | PYROMELLITIC DIIMIDES, PROCESSES FOR THEIR PREPARATION, THESE COMPOUNDS IN ORALLY ADMINISTRABLE FORM FOR USE IN INCREASING THE FEED EFFICIENCY OF A RUMINANT ANIMAL AND COMPOSITIONS FOR THIS PURPOSE CONTAINING THEM | MERCK & CO. INC. (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4289784-A | ASYMMETRICALLY SUBSTITUTED | MERCK & CO., INC. (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0010440-A1 | Pyromellitic diimides, processes for their preparation, these compounds in orally administrable form for use in increasing the feed efficiency of a ruminant animal and compositions for this purpose containing them | MERCK & CO. INC. (US) | 1980-04-30 | — | — | EP | disclosed |