Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.62 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261684 | 0.94 | TBXAS1 (0.64) | TBXAS1PLA2G4ACYP19A1MAPK1SMN1; SMN2 | |
| SCHEMBL9850492 | 0.87 | TBXAS1 (0.56) | TBXAS1CYP19A1SMN1; SMN2 | |
| SCHEMBL11255655 | 0.85 | TBXAS1 (0.56) | TBXAS1PLA2G4ACYP19A1HMOX1 | |
| SCHEMBL11375367 | 0.84 | TBXAS1 (0.64) | TBXAS1CYP19A1HMOX1 | |
| SCHEMBL10999217 | 0.82 | TBXAS1 (0.74) | TBXAS1CYP19A1 | |
| SCHEMBL11265550 | 0.81 | TBXAS1 (0.57) | TBXAS1PLA2G4ACYP19A1HMOX1 | |
| SCHEMBL10996907 | 0.81 | TBXAS1 (0.68) | TBXAS1HMOX1 | |
| SCHEMBL11257445 | 0.81 | TBXAS1 (0.58) | TBXAS1CYP19A1 | |
| SCHEMBL10996120 | 0.80 | TBXAS1 (0.67) | TBXAS1HMOX1 | |
| SCHEMBL10998799 | 0.80 | TBXAS1 (0.67) | TBXAS1HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |