Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.58 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262682 | 0.91 | TBXAS1 (0.67) | TBXAS1CYP19A1QPCTALDH1A1NAMPT | |
| SCHEMBL9850492 | 0.85 | TBXAS1 (0.56) | TBXAS1EGLN3CYP19A1QPCTALDH1A1 | |
| SCHEMBL6950296 | 0.85 | TBXAS1 (0.58) | TBXAS1EGLN3CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6948774 | 0.85 | POLB (0.60) | TBXAS1EGLN3CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL10247597 | 0.84 | CYP19A1 (0.72) | CYP19A1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL3255191 | 0.84 | TBXAS1 (0.78) | TBXAS1EGLN3CYP19A1 | |
| SCHEMBL6948539 | 0.84 | ALDH1A1 (0.62) | TBXAS1CYP19A1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL408241 | 0.84 | TBXAS1 (0.57) | TBXAS1EGLN3CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL412588 | 0.83 | CYP19A1 (0.70) | CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL411527 | 0.83 | TBXAS1 (0.76) | TBXAS1EGLN3CYP19A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |