Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 12/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196508 | 0.88 | ACE (0.55) | ACEFFAR2HTTPOLBLMNA | |
| SCHEMBL11267042 | 0.86 | ACE (0.53) | ACEFFAR2HTTPOLBGAA | |
| SCHEMBL11188904 | 0.83 | GAA (0.51) | ACEFFAR2HTTPOLBGAA | |
| SCHEMBL11110326 | 0.77 | ACE (0.51) | ACEFFAR2HTTLMNA | |
| SCHEMBL11102513 | 0.76 | ACE (0.68) | ACEFFAR2HTTPOLBGAA | |
| SCHEMBL11261862 | 0.76 | ACE (0.60) | ACEFFAR2HTTPOLBLMNA | |
| SCHEMBL11272933 | 0.74 | ACE (0.35) | ACEFFAR2 | |
| SCHEMBL11189446 | 0.73 | GAA (0.44) | ACEFFAR2POLBGAARAB9A | |
| SCHEMBL11075093 | 0.72 | ACE (0.54) | ACEFFAR2HTTPOLBGAA | |
| SCHEMBL11272093 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | disclosed |