Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.54 |
| ▸ | FFAR2 | O15552 | 12/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267042 | 0.83 | ACE (0.53) | ACEFFAR2HTTPOLBGAA | |
| SCHEMBL11191864 | 0.82 | ACE (0.53) | ACEFFAR2HTTPOLBGAA | |
| SCHEMBL11110326 | 0.81 | ACE (0.51) | ACEFFAR2HTTLMNA | |
| SCHEMBL11075099 | 0.81 | FFAR2 (0.54) | ACEFFAR2HTTLMNA | |
| SCHEMBL10999352 | 0.81 | ACE (0.52) | ACEFFAR2HTTPOLBLMNA | |
| SCHEMBL11195287 | 0.81 | ACE (0.52) | ACEFFAR2HTTPOLBLMNA | |
| SCHEMBL11102513 | 0.78 | ACE (0.68) | ACEFFAR2HTTPOLBGAA | |
| SCHEMBL3825312 | 0.77 | FFAR2 (0.52) | ACEFFAR2HTTPOLBGAA | |
| SCHEMBL3825310 | 0.77 | FFAR2 (0.52) | ACEFFAR2HTTPOLBGAA | |
| SCHEMBL11075090 | 0.77 | FFAR2 (0.52) | ACEFFAR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483861-A | Antihypertensive sulfur-containing compounds | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-11-20 | — | — | US | claimed |