Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FFAR2 | O15552 | 12/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267042 | 0.89 | ACE (0.53) | ACEFFAR2HTTLMNA | |
| SCHEMBL11102513 | 0.84 | ACE (0.68) | ACEFFAR2HTTLMNA | |
| SCHEMBL11066115 | 0.84 | ACE (0.71) | ACEKMT2AFFAR2HTTLMNA | |
| SCHEMBL10938815 | 0.84 | ACE (0.71) | ACEKMT2AFFAR2HTTLMNA | |
| SCHEMBL11075093 | 0.81 | ACE (0.54) | ACEFFAR2HTTLMNA | |
| SCHEMBL11110329 | 0.81 | ACE (0.48) | ACEFFAR2HTTLMNA | |
| SCHEMBL10995338 | 0.80 | ACE (0.47) | ACEKMT2AFFAR2LMNA | |
| SCHEMBL11061437 | 0.80 | KMT2A (0.58) | ACEKMT2AFFAR2LMNA | |
| SCHEMBL11110323 | 0.77 | FFAR2 (0.47) | ACEFFAR2HTTLMNA | |
| SCHEMBL11266045 | 0.77 | ACE (0.41) | ACEFFAR2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457935-A | ANGIOTENSIN-CONVERTING ENZYME INHIBITOR | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-07-03 | — | — | US | claimed |