Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 16/20 | 0.77 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11278073 | 0.98 | TBXAS1 (0.78) | TBXAS1EGLN3ALDH1A1TDP1 | |
| SCHEMBL11276271 | 0.87 | TBXAS1 (1.00) | TBXAS1EGLN3TDP1 | |
| Hydrochloric Acid SCHEMBL11275131 | 0.86 | TBXAS1 (1.00) | TBXAS1EGLN3TDP1 | |
| SCHEMBL11273054 | 0.80 | TBXAS1 (0.56) | TBXAS1ALDH1A1 | |
| Bicarbonate SCHEMBL29201379 | 0.79 | TBXAS1 (0.58) | TBXAS1EGLN3ALDH1A1 | |
| SCHEMBL4123092 | 0.78 | TBXAS1 (0.57) | TBXAS1 | |
| Acetic Acid SCHEMBL28843275 | 0.76 | TBXAS1 (0.55) | TBXAS1EGLN3ALDH1A1 | |
| SCHEMBL4342783 | 0.76 | TBXAS1 (0.54) | TBXAS1 | |
| SCHEMBL46043 | 0.75 | TBXAS1 (0.54) | TBXAS1EGLN3ALDH1A1 | |
| SCHEMBL14415940 | 0.74 | TBXAS1 (0.53) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4355170-A | ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | claimed |
| US-4355170-A | ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4256757-A | ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS; THROMBOSIS; ASTHMA; NERVOUS SYSTEM DISORDERS | ONO PHARMACEUTICAL CO., LTD. | 1981-03-17 | — | — | US | disclosed |