Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277878 | 0.89 | TBXAS1 (0.69) | TBXAS1ALDH1A1ABL1RIN1CYP1A2 | |
| SCHEMBL4123167 | 0.85 | TBXAS1 (0.48) | TBXAS1ALDH1A1ABL1RIN1KDM4E | |
| SCHEMBL11266178 | 0.80 | TBXAS1 (0.77) | TBXAS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11278073 | 0.78 | TBXAS1 (0.78) | TBXAS1ALDH1A1 | |
| SCHEMBL3278701 | 0.76 | TBXAS1 (0.44) | TBXAS1ALDH1A1KDM4EMEN1MITF | |
| SCHEMBL11274821 | 0.75 | TBXAS1 (0.72) | TBXAS1ALDH1A1KDM4EMEN1MITF | |
| SCHEMBL11274819 | 0.75 | TBXAS1 (0.72) | TBXAS1ALDH1A1KDM4EMEN1MITF | |
| SCHEMBL4342783 | 0.73 | TBXAS1 (0.54) | TBXAS1CYP1A2 | |
| Bicarbonate SCHEMBL29201379 | 0.73 | TBXAS1 (0.58) | TBXAS1ALDH1A1 | |
| SCHEMBL4123092 | 0.72 | TBXAS1 (0.57) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4355170-A | ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | claimed |
| US-4355170-A | ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4256757-A | ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS; THROMBOSIS; ASTHMA; NERVOUS SYSTEM DISORDERS | ONO PHARMACEUTICAL CO., LTD. | 1981-03-17 | — | — | US | disclosed |