Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675363 | 0.86 | POLB (0.60) | GABRA1GABRB2MAPTPOLBKDM4E | |
| SCHEMBL11278959 | 0.83 | GABRA1 (0.52) | GABRA1GABRB2MAPTALDH1A1TSHR | |
| SCHEMBL20175927 | 0.82 | MAPT (0.56) | GABRA1GABRB2MAPTPOLBKDM4E | |
| SCHEMBL3621894 | 0.82 | ADORA2A (0.50) | GABRA1GABRB2MAPTPOLBKDM4E | |
| SCHEMBL7768256 | 0.80 | TSHR (0.57) | MAPTPOLBKDM4EMEN1ALDH1A1 | |
| SCHEMBL31153347 | 0.80 | TSHR (0.57) | MAPTPOLBKDM4EMEN1ALDH1A1 | |
| SCHEMBL31038835 | 0.80 | PRKCI (0.60) | MAPTPOLBKDM4EMEN1ALDH1A1 | |
| SCHEMBL1822448 | 0.80 | PRKCI (0.60) | MAPTPOLBKDM4EMEN1ALDH1A1 | |
| SCHEMBL9628505 | 0.79 | KDM4E (0.53) | GABRA1GABRB2MAPTPOLBKDM4E | |
| SCHEMBL11278702 | 0.79 | GABRA1 (0.48) | GABRA1GABRB2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322304-A | ANTIOXIDANTS | PHILLIPS PETROLEUM COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
| US-4215229-A | AMNNICH REACTION, HYDROGENOLYSIS | KOPPERS COMPANY, INC. (US) | 1980-07-29 | — | — | US | disclosed |