Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.60 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.60 |
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266199 | 0.86 | GABRA1 (0.56) | POLBKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL11596899 | 0.79 | CYP1A2 (0.49) | TSHR | |
| SCHEMBL31411955 | 0.76 | GLA (0.45) | POLBKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL3790259 | 0.76 | KMT2A (0.61) | POLBKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL16153681 | 0.75 | PRKCI (0.39) | POLBKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL24129407 | 0.75 | PRKCI (0.66) | POLBKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL1822448 | 0.75 | PRKCI (0.60) | POLBKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL31038835 | 0.75 | PRKCI (0.60) | POLBKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL5805285 | 0.75 | HTT (0.59) | POLBKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL11519150 | 0.75 | POLB (0.59) | POLBKDM4EALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123978-A1 | METHODS OF DIAGNOSING, PREVENTING AND TREATING BONE MASS DISEASES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-10-08 | — | — | WO | disclosed |