Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266571 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2NPSR1TRPM8 | |
| SCHEMBL5578235 | 0.87 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2NPSR1TRPM8 | |
| SCHEMBL429369 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HTTSMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL5578163 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HTTSMN1; SMN2NPSR1HPGD | |
| SCHEMBL16975574 | 0.80 | PTGES (0.62) | ALDH1A1HTTSMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL16975570 | 0.80 | PTGES (0.62) | ALDH1A1HTTSMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL6987302 | 0.80 | KMT2A (0.53) | ALDH1A1SMN1; SMN2NPSR1NPC1KMT2A | |
| SCHEMBL6987299 | 0.80 | KMT2A (0.53) | ALDH1A1SMN1; SMN2NPSR1NPC1KMT2A | |
| SCHEMBL16971052 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HTTSMN1; SMN2NPSR1TP53 | |
| SCHEMBL31406407 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HTTSMN1; SMN2NPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |