Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | PREP | P48147 | 2/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685914 | 1.00 | GAA (0.67) | GAAHTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL30500954 | 0.92 | GAA (0.69) | GAAHTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL24658483 | 0.91 | GAA (0.61) | GAAHTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL11266194 | 0.89 | HTT (0.63) | GAAHTTLMNASMN1; SMN2SIGMAR1 | |
| SCHEMBL18152298 | 0.88 | HTT (0.65) | GAAHTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL14295143 | 0.87 | HTT (0.67) | GAAHTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL11263011 | 0.85 | PREP (0.59) | GAAHTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL7159251 | 0.85 | PREP (0.59) | GAAHTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL7298280 | 0.84 | SIGMAR1 (0.63) | GAAHTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL9222804 | 0.84 | GAA (0.52) | GAAHTTLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013790-B1 | CLAVULANIC ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1982-09-22 | — | — | EP | disclosed |
| EP-0013790-A1 | Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-08-06 | — | — | EP | disclosed |