Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258128 | 0.99 | SLC29A1 (0.40) | SLC29A1PKMHPGDTRPV1HTR4 | |
| SCHEMBL11262800 | 0.98 | SLC29A1 (0.39) | SLC29A1PKMHPGDTRPV1HTR4 | |
| SCHEMBL11262907 | 0.97 | SLC29A1 (0.38) | SLC29A1PKMHPGDTRPV1HTR4 | |
| SCHEMBL11255897 | 0.96 | HPGD (0.38) | SLC29A1PKMHPGDTRPV1HTR4 | |
| SCHEMBL11261238 | 0.93 | EPHX2 (0.40) | SLC29A1PKMKMT2AALDH1A1POLB | |
| SCHEMBL11270416 | 0.92 | EPHX2 (0.40) | SLC29A1PKMKMT2AALDH1A1POLB | |
| SCHEMBL11269348 | 0.90 | EPHX2 (0.40) | KMT2AALDH1A1POLBNPSR1 | |
| SCHEMBL11265822 | 0.85 | NPSR1 (0.34) | KMT2AMEN1ALDH1A1CYP2D6BCHE | |
| SCHEMBL11268609 | 0.85 | MAPT (0.35) | HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL11259600 | 0.85 | NPSR1 (0.34) | KMT2AMEN1ALDH1A1CYP2D6BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |