Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261238 | 0.97 | EPHX2 (0.40) | EPHX2L3MBTL1TP53EGFRERBB2 | |
| SCHEMBL11270416 | 0.96 | EPHX2 (0.40) | EPHX2L3MBTL1TP53EGFRERBB2 | |
| SCHEMBL11262907 | 0.93 | SLC29A1 (0.38) | POLBNPSR1KMT2A | |
| SCHEMBL11255897 | 0.92 | HPGD (0.38) | NPSR1KMT2A | |
| SCHEMBL11266856 | 0.90 | SLC29A1 (0.40) | POLBNPSR1KMT2AALDH1A1 | |
| SCHEMBL11258128 | 0.89 | SLC29A1 (0.40) | POLBKMT2AALDH1A1 | |
| SCHEMBL11262800 | 0.88 | SLC29A1 (0.39) | NPSR1KMT2AALDH1A1 | |
| Benzophenone SCHEMBL11262001 | 0.84 | L3MBTL1 (0.42) | L3MBTL1MAPTHTTSMN1; SMN2NPSR1 | |
| SCHEMBL11171100 | 0.84 | TTR (0.45) | KMT2AHIF1ACYP2A13LMNAFTO | |
| SCHEMBL11260654 | 0.83 | HPGD (0.33) | TP53MAPTSMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |