Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA3 | P07451 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259600 | 0.99 | NPSR1 (0.34) | NPSR1CA12CA1CA2CA4 | |
| SCHEMBL11271891 | 0.87 | HTT (0.36) | SMN1; SMN2TP53MAPTTDP1ALDH1A1 | |
| SCHEMBL11268609 | 0.87 | MAPT (0.35) | CA12CA1CA2CA4CA9 | |
| SCHEMBL11259321 | 0.86 | HTT (0.35) | SMN1; SMN2TP53MAPTTDP1ALDH1A1 | |
| SCHEMBL11261972 | 0.86 | TP53 (0.35) | CA12CA1CA2CA4CA9 | |
| SCHEMBL11266856 | 0.85 | SLC29A1 (0.40) | NPSR1ALDH1A1BCHEMEN1KMT2A | |
| SCHEMBL11271896 | 0.85 | TP53 (0.38) | CA12CA1CA2CA4CA9 | |
| SCHEMBL11258128 | 0.85 | SLC29A1 (0.40) | ALDH1A1BCHEMEN1KMT2ACYP2D6 | |
| SCHEMBL11261658 | 0.85 | TP53 (0.37) | CA12CA1CA2CA4CA9 | |
| SCHEMBL11271775 | 0.85 | TP53 (0.37) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |