Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 3/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273237 | 0.83 | HTT (0.49) | HTTSMN1; SMN2NPC1RAB9ARXFP1 | |
| SCHEMBL11302866 | 0.80 | HRH4 (0.47) | HTTSMN1; SMN2HRH4KMT2AMAPT | |
| SCHEMBL11271385 | 0.79 | HTT (0.46) | HTTSMN1; SMN2HRH4KMT2AMAPT | |
| SCHEMBL11266871 | 0.78 | HTT (0.59) | HTTSMN1; SMN2HRH4KMT2AMAPT | |
| SCHEMBL11263264 | 0.77 | HTT (0.75) | HTTSMN1; SMN2HRH4KMT2AMAPT | |
| SCHEMBL11277793 | 0.77 | HRH4 (0.44) | HTTSMN1; SMN2HRH4KMT2AMAPT | |
| SCHEMBL11263335 | 0.76 | HTT (0.49) | HTTSMN1; SMN2HRH4KMT2AMAPT | |
| SCHEMBL11272645 | 0.75 | HTT (0.43) | HTTSMN1; SMN2HRH4KMT2AMAPT | |
| SCHEMBL11275070 | 0.75 | HTT (0.71) | HTTSMN1; SMN2HRH4KMT2AMAPT | |
| SCHEMBL11270011 | 0.74 | HRH4 (0.42) | HTTSMN1; SMN2NPC1HRH4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018493-B1 | 2-SULFONYL-QUINOXALINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1982-12-01 | — | — | EP | disclosed |
| EP-0018493-A1 | 2-Sulfonyl-quinoxalines, processes for their preparation and their use as microbicides | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |