SCHEMBL11266968

SCHEMBL11266968

OC(Cc1ccc(Cl)cc1Cl)(Cn1ccnc1)c1ccc(Cl)cc1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGG1 O15527 1/20 0.57
CYP27B1 O15528 1/20 0.52
PTGS2 P35354 2/20 0.48
PDCD1 Q15116 1/20 0.47
CD274 Q9NZQ7 1/20 0.47
ADRA2C P18825 2/20 0.46
CYP3A4 P08684 5/20 0.46
CYP2C9 P11712 4/20 0.46
PGR P06401 2/20 0.46
CHRM2 P08172 2/20 0.46
ADRA2A P08913 2/20 0.46
ADORA3 P0DMS8 2/20 0.46
CYP2D6 P10635 2/20 0.46
CHRM1 P11229 2/20 0.46
ADRB3 P13945 2/20 0.46
IDO1 P14902 2/20 0.46
ADRA2B P18089 2/20 0.46
CHRM3 P20309 2/20 0.46
TACR2 P21452 2/20 0.46
DRD1 P21728 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11262774 0.93 OGG1 (0.51) OGG1CYP27B1PTGS2PDCD1CD274
Nitric Acid SCHEMBL11260394 0.92 CYP3A4 (0.53) OGG1CYP27B1PTGS2PDCD1CD274
SCHEMBL11268747 0.92 OGG1 (0.54) OGG1CYP27B1PTGS2PDCD1CD274
SCHEMBL11264045 0.88 OGG1 (0.49) OGG1CYP27B1PTGS2ADRA2CCYP3A4
SCHEMBL11275277 0.88 OGG1 (0.57) OGG1CYP27B1PTGS2PDCD1CD274
Hydrochloric Acid SCHEMBL11274202 0.87 OGG1 (0.56) OGG1CYP27B1PTGS2PDCD1CD274
Hydrochloric Acid SCHEMBL11266440 0.87 OGG1 (0.48) OGG1CYP27B1PTGS2ADRA2CCYP3A4
Nitric Acid SCHEMBL11268224 0.87 CYP3A4 (0.50) OGG1CYP27B1PTGS2PDCD1CD274
SCHEMBL10917880 0.86 OGG1 (0.61) OGG1CYP27B1PTGS2PDCD1CD274
SCHEMBL10916395 0.86 OGG1 (0.61) OGG1CYP27B1PTGS2PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358458-A BACTERICIDE, FUNGICIDES NORDMARK-WERKE GMBH (DE) 1982-11-09 US claimed