SCHEMBL11264045

SCHEMBL11264045

OC(Cc1ccc(Cl)cc1Cl)(Cn1ccnc1)c1ccc(Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGG1 O15527 1/20 0.49
ADRA2C P18825 2/20 0.46
CYP2C9 P11712 5/20 0.46
CYP3A4 P08684 4/20 0.46
PGR P06401 2/20 0.46
CHRM2 P08172 2/20 0.46
ADRA2A P08913 2/20 0.46
ADORA3 P0DMS8 2/20 0.46
CYP2D6 P10635 2/20 0.46
CHRM1 P11229 2/20 0.46
ADRB3 P13945 2/20 0.46
IDO1 P14902 2/20 0.46
ADRA2B P18089 2/20 0.46
CHRM3 P20309 2/20 0.46
TACR2 P21452 2/20 0.46
DRD1 P21728 2/20 0.46
ACHE P22303 2/20 0.46
SLC6A2 P23975 2/20 0.46
TBXAS1 P24557 2/20 0.46
HTR2A P28223 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11266440 0.99 OGG1 (0.48) OGG1ADRA2CCYP2C9CYP3A4PGR
SCHEMBL11264698 0.93 FNTA (0.48) OGG1ADRA2CCYP2C9CYP3A4PGR
SCHEMBL11264523 0.93 CYP11B1 (0.49) OGG1ADRA2CCYP2C9CYP3A4PGR
SCHEMBL11260328 0.92 OGG1 (0.47) OGG1ADRA2CCYP2C9CYP3A4PGR
SCHEMBL10813164 0.91 CYP19A1 (0.49) OGG1ADRA2CCYP2C9CYP3A4PGR
SCHEMBL11266968 0.88 OGG1 (0.57) OGG1ADRA2CCYP2C9CYP3A4PGR
Nitric Acid SCHEMBL11276057 0.87 CYP3A4 (0.50) OGG1ADRA2CCYP2C9CYP3A4PGR
SCHEMBL11181390 0.87 OGG1 (0.55) OGG1ADRA2CCYP2C9CYP3A4PGR
Nitric Acid SCHEMBL11267258 0.87 CYP3A4 (0.50) OGG1ADRA2CCYP2C9CYP3A4PGR
Nitric Acid SCHEMBL11269538 0.86 CYP3A4 (0.52) OGG1ADRA2CCYP2C9CYP3A4PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358458-A BACTERICIDE, FUNGICIDES NORDMARK-WERKE GMBH (DE) 1982-11-09 US claimed