Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11604784 | 1.00 | LMNA (0.49) | LMNAKDM4EPOLBMAPTBDKRB1 | |
| SCHEMBL14856285 | 1.00 | LMNA (0.49) | LMNAKDM4EPOLBMAPTBDKRB1 | |
| SCHEMBL11589402 | 0.85 | NTRK1 (0.47) | LMNABDKRB1NTRK1RAB9AKMT2A | |
| SCHEMBL11262948 | 0.84 | BDKRB1 (0.42) | LMNABDKRB1NTRK1TSHRRAB9A | |
| SCHEMBL11603585 | 0.84 | BDKRB1 (0.42) | LMNABDKRB1NTRK1TSHRRAB9A | |
| SCHEMBL8695216 | 0.84 | P2RX7 (0.51) | LMNAKDM4EPOLBMAPTMTNR1A | |
| SCHEMBL20252628 | 0.84 | P2RX7 (0.51) | LMNAKDM4EPOLBMAPTMTNR1A | |
| SCHEMBL11589333 | 0.84 | KMT2A (0.55) | KDM4EBDKRB1CA1CA2NTRK1 | |
| SCHEMBL11593014 | 0.81 | NTRK1 (0.47) | LMNAKDM4EPOLBMAPTBDKRB1 | |
| SCHEMBL11592497 | 0.81 | HTT (0.50) | BDKRB1NTRK1MTNR1AKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091018-A | ANIMAL GROWTH PROMOTERS | AMERICAN CYANAMID COMPANY (US) | 1978-05-23 | — | — | US | claimed |
| US-4332724-A | OXIDATION IN PRESENCE OF COBALT CATALYST | AMERICAN CYANAMID CO. (US) | 1982-06-01 | — | — | US | disclosed |
| US-4254268-A | OXIDIZED BY POTASSIUM PERMANGANATE | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4199510-A | Process for oxidation of 4-amidotetrahydrobenzo [b]-thiophenes to 7-keto derivatives with cobaltic salts | AMERICAN CYANAMID COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| US-4091018-A | ANIMAL GROWTH PROMOTERS | AMERICAN CYANAMID COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
| US-4089976-A | Synthesis of 1,2,3,4-tetrahydro-4-oxo-[or oxy-]-1-naphthylureas as novel growth-promoting compounds for animals | AMERICAN CYANAMID COMPANY (US) | 1978-05-16 | — | — | US | disclosed |
| US-4049717-A | INTERMEDIATES FOR UREAS AND THIOUREAS | AMERICAN CYANAMID COMPANY (US) | 1977-09-20 | — | — | US | disclosed |