Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NSD1 | Q96L73 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22130266 | 0.85 | HSD17B10 (0.56) | HSD17B10ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL16994729 | 0.81 | ALDH1A1 (0.71) | HSD17B10ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL19782965 | 0.79 | CYP3A4 (0.54) | HSD17B10ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL6058374 | 0.77 | ALDH1A1 (0.44) | HSD17B10ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL6234853 | 0.77 | ALDH1A1 (0.61) | HSD17B10ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL20582165 | 0.77 | HSD17B10 (0.61) | HSD17B10ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL1913640 | 0.77 | HSD17B10 (1.00) | HSD17B10ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL21091214 | 0.77 | HSD17B10 (0.72) | HSD17B10ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL31218402 | 0.77 | HSD17B10 (0.61) | HSD17B10ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL5247755 | 0.77 | HSD17B10 (0.72) | HSD17B10ALDH1A1LMNASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |