Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275928 | 0.81 | HRH3 (0.40) | MEN1KMT2AGAA | |
| SCHEMBL11833807 | 0.81 | NPC1 (0.51) | NPC1MAPTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL11260218 | 0.80 | MAPT (0.39) | NPC1MAPTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL11260968 | 0.72 | RECQL (0.34) | RECQL | |
| SCHEMBL11263670 | 0.72 | MAPT (0.42) | NPC1MAPTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL11266410 | 0.71 | TSHR (0.63) | MAPTALDH1A1SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL22153203 | 0.70 | PDE10A (0.46) | KMT2AGPR119CNR2 | |
| SCHEMBL11584879 | 0.70 | NPC1 (0.68) | NPC1MAPTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL11668633 | 0.69 | NPC1 (0.43) | NPC1MAPTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL29738590 | 0.67 | NPC1 (0.55) | NPC1MAPTALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327095-A | TRANQUICIZERS, ANTICONVULSANTS DECONTRACTURANTS AND HYPNOGENIC AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1982-04-27 | — | — | US | disclosed |