SCHEMBL11260968

SCHEMBL11260968

COC1CSC2=C(SC1)C(=O)N(c1ccc3ccc(C)nc3n1)C2=O

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11263616 0.87
SCHEMBL11843436 0.83 ALDH1A1 (0.41) RECQL
SCHEMBL11262228 0.81 NPC1 (0.31)
SCHEMBL11275928 0.76 HRH3 (0.40)
SCHEMBL14336359 0.73 RECQL (0.42) RECQL
SCHEMBL11262906 0.73 ADORA3 (0.42) RECQL
SCHEMBL11267038 0.72 NPC1 (0.43) RECQL
SCHEMBL11836641 0.72 ALDH1A1 (0.42)
SCHEMBL11266030 0.69 FPR2 (0.30)
SCHEMBL11843433 0.69 RECQL (0.36) RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4327095-A TRANQUICIZERS, ANTICONVULSANTS DECONTRACTURANTS AND HYPNOGENIC AGENTS RHONE-POULENC INDUSTRIES (FR) 1982-04-27 US disclosed