Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846739 | 0.82 | HTR3A (0.47) | HRH3HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL11264550 | 0.82 | HRH3 (0.35) | HRH3HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL11267038 | 0.81 | NPC1 (0.43) | KMT2AMEN1GAA | |
| SCHEMBL11263616 | 0.80 | — | — | |
| SCHEMBL11260968 | 0.76 | RECQL (0.34) | — | |
| SCHEMBL11277201 | 0.74 | ADORA3 (0.47) | HRH3HTR3AHRH4PDE10A | |
| SCHEMBL11668986 | 0.72 | HTR3A (0.40) | HRH3HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL11486318 | 0.69 | HTR3A (0.46) | HRH3HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL11833872 | 0.65 | HRH3 (0.40) | HRH3HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL11266030 | 0.63 | FPR2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327095-A | TRANQUICIZERS, ANTICONVULSANTS DECONTRACTURANTS AND HYPNOGENIC AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1982-04-27 | — | — | US | disclosed |