Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267067 | 0.85 | KMT2A (0.41) | KMT2AKDM4EPOLBGRIN2DGRIN3B | |
| SCHEMBL11266609 | 0.84 | MLYCD (0.40) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11276944 | 0.81 | NR1H2 (0.42) | KMT2AMLYCDSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11264839 | 0.80 | NR1H2 (0.35) | KMT2AMLYCDSMN1; SMN2MEN1TSHR | |
| SCHEMBL11278797 | 0.80 | MEN1 (0.38) | KMT2AMLYCDSMN1; SMN2MEN1TSHR | |
| SCHEMBL6212685 | 0.80 | SMN1; SMN2 (0.54) | KMT2APOLBMLYCDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11262158 | 0.78 | MLYCD (0.39) | KMT2AMLYCDSMN1; SMN2MEN1TSHR | |
| Hydrochloric Acid SCHEMBL11266398 | 0.78 | NR1H2 (0.34) | KMT2AMLYCDSMN1; SMN2MEN1TSHR | |
| SCHEMBL3431607 | 0.77 | SMN1; SMN2 (0.46) | KMT2AMLYCDSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11272364 | 0.77 | NR1H2 (0.35) | KMT2APOLBMLYCDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267193-A | N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1981-05-12 | — | — | US | claimed |
| US-4322434-A | N-Substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4267193-A | N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |