Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | HTR2A | P28223 | 18/20 | 0.67 |
| ▸ | HTR2C | P28335 | 17/20 | 0.67 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 4/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR5A | P47898 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11314589 | 0.89 | KMT2A (0.77) | KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL11256819 | 0.87 | KMT2A (0.74) | KMT2AHTR2AHTR2CMAPKAPK2HTR2B | |
| SCHEMBL11317821 | 0.87 | KMT2A (0.71) | KMT2AHTR2AHTR2C | |
| SCHEMBL8321835 | 0.84 | KMT2A (0.70) | KMT2AHTR2AHTR2CMAPKAPK2HTR7 | |
| Hydrochloric Acid SCHEMBL11249624 | 0.84 | KMT2A (0.72) | KMT2AHTR2AHTR2CMAPKAPK2HTR7 | |
| SCHEMBL28652272 | 0.83 | MAPKAPK2 (0.69) | KMT2AHTR2AHTR2CMAPKAPK2HTR2B | |
| SCHEMBL4105569 | 0.83 | KMT2A (0.52) | KMT2AHTR2AHTR2CMAPKAPK2HTR2B | |
| SCHEMBL30923475 | 0.83 | MAPKAPK2 (0.69) | KMT2AHTR2AHTR2CMAPKAPK2HTR2B | |
| SCHEMBL944770 | 0.78 | HTR2A (0.68) | KMT2AHTR2AHTR2CMAPKAPK2 | |
| Hydrochloric Acid SCHEMBL7683967 | 0.76 | HTR2A (0.54) | KMT2AHTR2AHTR2CMAPKAPK2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336256-A | TREATMENT OF ANOXIA, DEPRESSION AND IN PSYCHOTROPIC THERAPY | SYNTHELABO (FR) | 1982-06-22 | — | — | US | disclosed |
| US-4272539-A | ANOXIA, ANTIDEPRESSANTS | SYNTHELABO (FR) | 1981-06-09 | — | — | US | disclosed |