Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.69 |
| ▸ | HTR2A | P28223 | 12/20 | 0.60 |
| ▸ | HTR2C | P28335 | 12/20 | 0.60 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30923475 | 1.00 | MAPKAPK2 (0.69) | MAPKAPK2HTR2AHTR2CMAPKAPK5HTR2B | |
| SCHEMBL23070186 | 0.87 | MAPKAPK2 (0.69) | MAPKAPK2HTR2AHTR2CMAPKAPK5HTR2B | |
| Hydrochloric Acid SCHEMBL11272723 | 0.86 | MAPKAPK2 (0.73) | MAPKAPK2HTR2AHTR2CMAPKAPK5HTR2B | |
| SCHEMBL10481507 | 0.84 | MAPKAPK2 (0.67) | MAPKAPK2MAPKAPK5KMT2A | |
| SCHEMBL273473 | 0.84 | MAPKAPK2 (0.67) | MAPKAPK2MAPKAPK5KMT2A | |
| SCHEMBL11267091 | 0.83 | KMT2A (0.74) | MAPKAPK2HTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL6240455 | 0.82 | MAPKAPK2 (1.00) | MAPKAPK2HTR2AHTR2CMAPKAPK5HTR2B | |
| SCHEMBL11270750 | 0.81 | MAPKAPK2 (0.74) | MAPKAPK2HTR2AHTR2CMAPKAPK5HTR2B | |
| SCHEMBL31328292 | 0.80 | MAPT (0.77) | KMT2A | |
| SCHEMBL9687220 | 0.80 | MAPKAPK2 (0.50) | MAPKAPK2HTR2AHTR2CMAPKAPK5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307806-A | Beta-carboline selective monoamine oxidase B inhibitor and pharmaceutical application thereof | 陈冬寅 | 2021-08-27 | — | — | CN | disclosed |