Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 5/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256789 | 0.88 | EGLN1 (0.36) | POLBPDE5AGUSBPDE3BPDE3A | |
| SCHEMBL11257919 | 0.87 | PDE5A (0.34) | POLBPDE5AGUSBPDE3BPDE3A | |
| SCHEMBL11253838 | 0.86 | TRPA1 (0.36) | POLBPDE5AS1PR1GUSBPDE3B | |
| SCHEMBL11252271 | 0.84 | POLB (0.36) | POLBNPSR1PDE3BPDE3APDE2A | |
| SCHEMBL11249168 | 0.84 | PDE5A (0.32) | POLBPDE5AGUSBPDE3BPDE3A | |
| SCHEMBL11241670 | 0.84 | TRPA1 (0.33) | POLBPDE5AGUSBPDE3BPDE3A | |
| SCHEMBL11259216 | 0.83 | PDE3B (0.33) | POLBPDE5AGUSBPDE3BPDE3A | |
| SCHEMBL11255145 | 0.82 | PDE5A (0.33) | NPSR1PDE5AGUSBF10PLG | |
| SCHEMBL11256153 | 0.81 | F10 (0.33) | POLBPDE5AF10PLGPLAU | |
| SCHEMBL11252458 | 0.81 | HTR2A (0.33) | NPSR1PDE5AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |