Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 7/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.32 |
| ▸ | PDE6A | P16499 | 1/20 | 0.32 |
| ▸ | PDE6G | P18545 | 1/20 | 0.32 |
| ▸ | PDE6B | P35913 | 1/20 | 0.32 |
| ▸ | PDE6C | P51160 | 1/20 | 0.32 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252458 | 0.90 | HTR2A (0.33) | PDE5APDE6DPDE6APDE6GPDE6B | |
| SCHEMBL11256789 | 0.86 | EGLN1 (0.36) | PDE5AALDH1A1MAPTHTTGUSB | |
| SCHEMBL11257919 | 0.85 | PDE5A (0.34) | PDE5AMAPTLMNAGUSBF10 | |
| SCHEMBL11244450 | 0.84 | PTGS1 (0.33) | PDE5APDE6DPDE6APDE6GPDE6B | |
| SCHEMBL11241670 | 0.84 | TRPA1 (0.33) | PDE5AMAPTGUSBF10PLG | |
| SCHEMBL11253838 | 0.84 | TRPA1 (0.36) | PDE5AMAPTGUSBF10PLG | |
| SCHEMBL11267101 | 0.82 | POLB (0.36) | PDE5ANPSR1MAPTLMNAGUSB | |
| SCHEMBL11249168 | 0.82 | PDE5A (0.32) | PDE5AMAPTGUSBF10PLG | |
| SCHEMBL11259216 | 0.81 | PDE3B (0.33) | PDE5AMAPTGUSBF10PLG | |
| SCHEMBL11256153 | 0.79 | F10 (0.33) | PDE5ALRRK2MAPTF10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |