Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266675 | 0.84 | CACNA1F (0.62) | NPSR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11262288 | 0.79 | CACNA1F (0.50) | CACNA1FCACNA1DCACNA1SCACNA1CTSHR | |
| SCHEMBL3026966 | 0.73 | ABCC1 (0.71) | SMN1; SMN2KDM4ECACNA1FCACNA1DCACNA1S | |
| SCHEMBL11268439 | 0.73 | NPSR1 (0.47) | NPSR1HPGDKDM4EGAATSHR | |
| SCHEMBL11252563 | 0.73 | CACNA1F (0.43) | NPSR1KDM4EGAACACNA1FCACNA1D | |
| SCHEMBL11260512 | 0.73 | CACNA1F (0.53) | NPSR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11773488 | 0.72 | CACNA1F (0.56) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL11264562 | 0.72 | CACNA1F (0.61) | NPSR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11004012 | 0.72 | NPSR1 (0.50) | NPSR1SMN1; SMN2HPGDKDM4EGAA | |
| SCHEMBL11877354 | 0.71 | CACNA1F (0.54) | CACNA1FCACNA1DCACNA1SCACNA1CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348395-A | 1,4-Dihydropyridazine compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |