Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568225 | 0.85 | MAOA (0.38) | NPSR1TSHRKDM4EHPGDSLC6A3 | |
| SCHEMBL11256475 | 0.79 | SLC6A3 (0.47) | NPSR1KDM4ESLC6A3ALDH1A1GLA | |
| SCHEMBL11254571 | 0.74 | CACNA1B (0.47) | SLC6A3GAAPOLB | |
| SCHEMBL11267200 | 0.73 | NPSR1 (0.49) | NPSR1TSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL11259253 | 0.73 | SLC6A3 (0.46) | NPSR1SLC6A3ALDH1A1GAALMNA | |
| SCHEMBL11332331 | 0.70 | SLC6A3 (0.38) | NPSR1SLC6A3ALDH1A1LMNAKMT2A | |
| SCHEMBL10516757 | 0.70 | POLB (0.52) | NPSR1TSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL10678279 | 0.68 | CACNA1B (0.55) | SLC6A3 | |
| SCHEMBL9085895 | 0.68 | CACNA1B (0.57) | TSHRMAPK1LMNAKMT2AMEN1 | |
| SCHEMBL10113390 | 0.68 | KMT2A (0.73) | TSHRKDM4EALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348395-A | 1,4-Dihydropyridazine compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |