Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942091 | 0.85 | ALDH1A1 (0.61) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL29391169 | 0.85 | ALDH1A1 (0.61) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL30116206 | 0.85 | ALDH1A1 (0.61) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL18185050 | 0.85 | ALDH1A1 (0.61) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL7995962 | 0.85 | ALDH1A1 (0.61) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL18185067 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL8361517 | 0.83 | TDP1 (0.58) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL19301918 | 0.82 | ALDH1A1 (0.57) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL11048268 | 0.82 | ALDH1A1 (0.57) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL1126997 | 0.82 | ALDH1A1 (0.57) | ALDH1A1TDP1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |