SCHEMBL1126997

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126993	1.00	ALDH1A1 (0.57)	ALDH1A1TDP1L3MBTL1TSHRAR
	SCHEMBL8575821	0.89	ALDH1A1 (0.56)	ALDH1A1TDP1L3MBTL1TSHRAR
	SCHEMBL945131	0.84	ALDH1A1 (0.50)	ALDH1A1TDP1L3MBTL1TSHRAR
	SCHEMBL7995962	0.84	ALDH1A1 (0.61)	ALDH1A1TDP1L3MBTL1TSHRAR
	SCHEMBL29391169	0.84	ALDH1A1 (0.61)	ALDH1A1TDP1L3MBTL1TSHRAR
	SCHEMBL6775823	0.83	ALDH1A1 (0.49)	ALDH1A1TDP1L3MBTL1TSHRLMNA
	SCHEMBL8683168	0.83	CA12 (0.55)	ALDH1A1TDP1TSHRLMNASMN1; SMN2
	SCHEMBL3535123	0.83	GPR35 (0.54)	ALDH1A1TDP1L3MBTL1TSHRKMT2A
	SCHEMBL8579967	0.83	ALDH1A1 (0.46)	ALDH1A1TDP1L3MBTL1TSHRAR
	SCHEMBL1126722	0.82	ALDH1A1 (0.62)	ALDH1A1TDP1L3MBTL1ARKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.