Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267238 | 1.00 | HDAC1 (0.43) | HDAC1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL7381899 | 0.81 | CES2 (0.52) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL11345879 | 0.80 | CES2 (0.50) | ALDH1A1KMT2AHIF1AMAPTCYP11B1 | |
| SCHEMBL7381695 | 0.80 | MAPT (0.41) | ALDH1A1KMT2AMEN1HIF1AMAPT | |
| SCHEMBL9475635 | 0.80 | CYP11B1 (0.58) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL11345881 | 0.80 | CES2 (0.50) | ALDH1A1KMT2AHIF1AMAPTCYP11B1 | |
| SCHEMBL5318227 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1HIF1AMAPT | |
| SCHEMBL7383383 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1HIF1AMAPT | |
| SCHEMBL7377209 | 0.77 | CYP11B1 (0.57) | ALDH1A1KMT2AMAPTHPGDCYP11B1 | |
| SCHEMBL10808087 | 0.77 | HTT (0.49) | ALDH1A1KMT2AMEN1HTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |