SCHEMBL11267302

SCHEMBL11267302

CCCCOCO[Si](CC)(CCCl)OCOCCCC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11265043 0.80
SCHEMBL17937709 0.75 TSHR (0.40) TSHRTDP1
SCHEMBL28957445 0.71 HTT (0.36) TDP1
SCHEMBL9166007 0.71
SCHEMBL707587 0.71 ADRB2 (0.38) TSHR
SCHEMBL11265167 0.69 TSHR (0.40) TSHRTDP1
SCHEMBL5833984 0.69 ADRB2 (0.36) TSHR
SCHEMBL703938 0.69 ADRB2 (0.36) TSHR
SCHEMBL707072 0.69 ADRB2 (0.36) TSHR
SCHEMBL5833540 0.69 ADRB2 (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4332612-A N-METHYL-2-PYRROLIDONE AND A HALOALKYL SILANE GAF CORPORATION (US) 1982-06-01 US disclosed