Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966000 | 0.84 | TSHR (0.75) | TSHRTHRBALDH1A1 | |
| SCHEMBL8471607 | 0.82 | TSHR (0.61) | TSHRTHRBALDH1A1 | |
| SCHEMBL2788400 | 0.81 | TSHR (0.64) | TSHRTHRBALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL7766598 | 0.80 | TSHR (0.69) | TSHRTHRBALDH1A1 | |
| Hydrochloric Acid SCHEMBL1362589 | 0.79 | TSHR (0.62) | TSHRTHRBALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL10494078 | 0.79 | TSHR (0.67) | TSHRTHRBALDH1A1 | |
| SCHEMBL538796 | 0.79 | TSHR (0.67) | TSHRTHRBALDH1A1 | |
| Trimethylammonium SCHEMBL11665410 | 0.79 | TSHR (0.88) | TSHRTHRBALDH1A1 | |
| SCHEMBL13779875 | 0.79 | TSHR (0.61) | TSHRTHRBALDH1A1 | |
| SCHEMBL23494255 | 0.77 | TSHR (0.64) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314800-A | DIALKYLAMINO-SUBSTITUTED ACRYLATE-ACRYLIC ACID INTERPOLYMER | ROHM GMBH (DE) | 1982-02-09 | — | — | US | disclosed |