Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 known ✓ | P30926 | 6/20 | 0.39 |
| ▸ | CHRNA3 known ✓ | P32297 | 5/20 | 0.39 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 8/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788400 | 0.98 | TSHR (0.64) | TSHRTHRBCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL3407482 | 0.82 | TSHR (0.55) | TSHRTHRBCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL25013244 | 0.81 | TSHR (0.62) | TSHRTHRBALDH1A1 | |
| Trimethylammonium SCHEMBL534138 | 0.81 | TSHR (0.62) | TSHRTHRBALDH1A1 | |
| SCHEMBL4979161 | 0.80 | TSHR (0.56) | TSHRTHRBALDH1A1 | |
| Trimethylammonium SCHEMBL11665410 | 0.80 | TSHR (0.88) | TSHRTHRBALDH1A1 | |
| SCHEMBL13779875 | 0.80 | TSHR (0.61) | TSHRTHRBALDH1A1 | |
| SCHEMBL8471607 | 0.80 | TSHR (0.61) | TSHRTHRBALDH1A1 | |
| Ethylene SCHEMBL27833189 | 0.79 | TSHR (0.95) | TSHRTHRBALDH1A1 | |
| SCHEMBL3799578 | 0.79 | CHRNB2 (0.59) | TSHRTHRBCHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874614-B | Polyamide composition and preparation method and application thereof | 江苏金发科技新材料有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-114874614-A | Polyamide composition and preparation method and application thereof | 江苏金发科技新材料有限公司 | 2022-08-09 | — | — | CN | claimed |
| CN-114874614-B | Polyamide composition and preparation method and application thereof | 江苏金发科技新材料有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117467161-A | Zwitterionic polymer/agar composite hydrogel capable of being printed in 3D mode and preparation method and application thereof | 湖南汽车工程职业学院 | 2024-01-30 | — | — | CN | disclosed |
| CN-115976853-A | Polyurea elastomer composite fabric and manufacturing method thereof | 西京学院 | 2023-04-18 | — | — | CN | disclosed |
| CN-114874614-A | Polyamide composition and preparation method and application thereof | 江苏金发科技新材料有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114426500-A | Method for preparing ketoxime by ketoammoximation | 中国石油化工股份有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-111388351-B | Thickener composition comprising agarose and xanthan gum | 上海家化联合股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-108273478-B | Formaldehyde removal composition and product | 李怀玉 | 2021-03-02 | — | — | CN | disclosed |
| CN-111388351-A | Thickener composition comprising agarose and xanthan gum | 上海家化联合股份有限公司 | 2020-07-10 | — | — | CN | disclosed |
| US-10459358-B2 | Method for producing a toner | ZEON CORPORATION (JP) | 2019-10-29 | — | — | US | disclosed |
| EP-0620481-B1 | Silver Halide photographic light-sensitive material | KONISHIROKU PHOTO IND (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-5415987-A | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| US-5393652-A | Support with emulsion layer and protective layers containing polyethylene naphthalenedicarboxylate, for prevention of pressure fogging and desensitization in high speed automatic processing | KONICA CORPORATION (JP) | 1995-02-28 | — | — | US | disclosed |
| US-5370983-A | Comprising water-insoluble, organic solvent soluble polymer and hydrophobic photographically useful component; polymer having carbonyl group, mainly esters and amides | FUJI PHOTO FILM CO., LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0620481-A2 | Silver Halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1994-10-19 | — | — | EP | disclosed |
| EP-0619514-A1 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1994-10-12 | — | — | EP | disclosed |
| EP-0615158-A1 | A silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1994-09-14 | — | — | EP | disclosed |
| EP-0256531-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | Fuji Photo Film Co., Ltd. (JP) | 1992-11-25 | — | — | EP | disclosed |
| US-4946770-A | CYAN DYE IMAGES EXCELLENT IN PRESERAVIBILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |